Endocrine Abstracts

Background: Oxidized low-density lipoprotein (Ox-LDL) is a key factor in the development of arteriosclerosis. It can cause endothelial dysfunction and augment lipid accumulation within the arterial wall. Increased oxidative stress in diabetes contributes to this process. Ox-LDL is a highly immunogenic molecule and it is not clear whether oxidized LDL antibodies (OLAB) are pathogenic or protective in arteriosclerosis? The aim of this study was to evaluate Ox-LDL and its antibod...

The endothelial dysfunction and atherosclerosis. Recent studies have demonstrated that the amount of oxidized LDL (Ox-LDL) in plasma is correlated with IR in non-diabetic population. The intent of this study was to evaluate correlation of Ox-LDL and IR in diabetic patients, and to compare it with normal individuals.Methods: A total of 150 individuals aged 40 to 65 years were studied including 81 type 2 diabetic patients and 69 non-diabetic sex and BMI ma...

Aims/Introduction: To evaluate the impact of diabetes mellitus on the incidence of related micro- and macrovascular outcomes as well as cost analysis in people with type 2 diabetes mellitus.Materials and methods: In a cohort study, registered patients with type 2 diabetes mellitus were followed for 10 years at a tertiary care center. The type of medications and clinical data were extracted from patients’ archives. Incidence of mortality, micro- and ...